The categorization of airflow relies on a number of similarity parameters, which allow the simplification of a nearly infinite number of test cases into groups of similarity. For transonic and compressible flow, the Mach và Reynolds numbers alone allow good categorization of many flow cases.

Hypersonic flows, however, require other similarity parameters. First, the analytic equations for the oblique shock angle become nearly independent of Mach number at high (~>10) Mach numbers. Second, the formation of strong shocks around aerodynamic bodies means that the freestream Reynolds number is less useful as an estimate of the behavior of the boundary layer over a body (although it is still important). Finally, the increased temperature of hypersonic flows mean that real gas effects become important. For this reason, research in hypersonics is often referred to as aerothermodynamics, rather than aerodynamics.

The introduction of real gas effects means that more variables are required to describe the full state of a gas. Whereas a stationary gas can be described by three variables (pressure, temperature, adiabatic index), and a moving gas by four (flow velocity), a hot gas in chemical equilibrium also requires state equations for the chemical components of the gas, and a gas in nonequilibrium solves those state equations using time as an extra variable. This means that for a nonequilibrium flow, something between 10 and 100 variables may be required to describe the state of the gas at any given time. Additionally, rarefied hypersonic flows (usually defined as those with a Knudsen number above 0.1) do not follow the Navier–Stokes equations.

Hypersonic flows are typically categorized by their total energy, expressed as total enthalpy (MJ/kg), total pressure (kPa-MPa), stagnation pressure (kPa-MPa), stagnation temperature (K), or flow velocity (km/s).

Wallace D. Hayes developed a similarity parameter, similar to the Whitcomb area rule, which allowed similar configurations to be compared.